6SBU
X-ray Structure of Human LDHA with an Allosteric Inhibitor (Compound 3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | L-lactate dehydrogenase A chain | polymer | 332 | 36660.5 | 8 | UniProt (P00338) Pfam (PF00056) Pfam (PF02866) In PDB | Homo sapiens (Human) | LDH-A,Cell proliferation-inducing gene 19 protein,LDH muscle subunit,LDH-M,Renal carcinoma antigen NY-REN-59 |
| 2 | A, B, C, D, E... | 4-[[4-[(5-chloranylthiophen-2-yl)carbonylamino]-1,3-bis(oxidanylidene)isoindol-2-yl]methyl]benzoic acid | non-polymer | 440.9 | 8 | Chemie (L5N) | |||
| 3 | A, E | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 2 | Chemie (NAI) | |||
| 4 | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 2 - 332 (UniProt: P00338)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 293284.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 4857.7 | |
| All* | Total formula weight | 298141.9 |
