6SBI

X-ray structure of murine Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) in complex with inhibitor oxalate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Acylpyruvase FAHD1, mitochondrial	polymer	265	29413.0	4	UniProt (Q8R0F8) Pfam (PF01557) In PDB	Mus musculus (Mouse)	Fumarylacetoacetate hydrolase domain-containing protein 1,Oxaloacetate decarboxylase,OAA decarboxylase
2	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	A, C	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
4	A, B, C, D	CHLORIDE ION	non-polymer		35.5	9	Chemie (CL)
5	A, B, C, D	OXALATE ION	non-polymer		88.0	4	Chemie (OXL)
6		water	water		18.0	33	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 227 (UniProt: Q8R0F8)

PDB	External Database	Details
Met -37	-	initiating methionine
His -36	-	expression tag
His -35	-	expression tag
His -34	-	expression tag
His -33	-	expression tag
His -32	-	expression tag
His -31	-	expression tag
Ser -30	-	expression tag
Ser -29	-	expression tag
Gly -28	-	expression tag
Leu -27	-	expression tag
Val -26	-	expression tag
Pro -25	-	expression tag
Arg -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Met -20	-	expression tag
Lys -19	-	expression tag
Glu -18	-	expression tag
Thr -17	-	expression tag
Ala -16	-	expression tag
Ala -15	-	expression tag
Ala -14	-	expression tag
Lys -13	-	expression tag
Phe -12	-	expression tag
Glu -11	-	expression tag
Arg -10	-	expression tag
Gln -9	-	expression tag
His -8	-	expression tag
Met -7	-	expression tag
Asp -6	-	expression tag
Ser -5	-	expression tag
Pro -4	-	expression tag
Asp -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	117652.0
Non-Polymers*	Number of molecules	19
	Total formula weight	846.6
All*	Total formula weight	118498.5

*Water molecules are not included.