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6SBI

X-ray structure of murine Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) in complex with inhibitor oxalate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Acylpyruvase FAHD1, mitochondrialpolymer26529413.04UniProt (Q8R0F8)
Pfam (PF01557)
Mus musculus (Mouse)Fumarylacetoacetate hydrolase domain-containing protein 1,Oxaloacetate decarboxylase,OAA decarboxylase
2E, K, O, U
(A, B, C, D)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
3F, P
(A, C)
POTASSIUM IONnon-polymer39.12Chemie (K)
4G, H, I, L, M...
(A, B, C, D)
CHLORIDE IONnon-polymer35.59Chemie (CL)
5J, N, T, W
(A, B, C, D)
OXALATE IONnon-polymer88.04Chemie (OXL)
6AA, X, Y, Z
(D, A, B, C)
waterwater18.033Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 227 (UniProt: Q8R0F8)
PDBExternal DatabaseDetails
Met -37-initiating methionine
His -36-expression tag
His -35-expression tag
His -34-expression tag
His -33-expression tag
His -32-expression tag
His -31-expression tag
Ser -30-expression tag
Ser -29-expression tag
Gly -28-expression tag
Leu -27-expression tag
Val -26-expression tag
Pro -25-expression tag
Arg -24-expression tag
Gly -23-expression tag
Ser -22-expression tag
Gly -21-expression tag
Met -20-expression tag
Lys -19-expression tag
Glu -18-expression tag
Thr -17-expression tag
Ala -16-expression tag
Ala -15-expression tag
Ala -14-expression tag
Lys -13-expression tag
Phe -12-expression tag
Glu -11-expression tag
Arg -10-expression tag
Gln -9-expression tag
His -8-expression tag
Met -7-expression tag
Asp -6-expression tag
Ser -5-expression tag
Pro -4-expression tag
Asp -3-expression tag
Leu -2-expression tag
Gly -1-expression tag
Thr 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight117652.0
Non-Polymers*Number of molecules19
Total formula weight846.6
All*Total formula weight118498.5
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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