6S9B
EGFR-KINASE IN COMPLEX WITH COMPOUND 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Epidermal growth factor receptor | polymer | 326 | 37147.0 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (Human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
2 | B (A) | 3-fluoranyl-~{N}-[1-(2-methyl-2-oxidanyl-propyl)benzimidazol-2-yl]-5-pyridin-3-yl-benzamide | non-polymer | 404.4 | 1 | Chemie (L1H) |
Sequence modifications
A: 697 - 1022 (UniProt: P00533)
PDB | External Database | Details |
---|---|---|
Met 790 | Thr 790 | engineered mutation |
Arg 858 | Leu 858 | engineered mutation |
Ala 865 | Glu 865 | engineered mutation |
Ala 866 | Glu 866 | engineered mutation |
Ala 867 | Lys 867 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37147.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 404.4 | |
All* | Total formula weight | 37551.5 |