6S6Y
X-ray crystal structure of the formyltransferase/hydrolase complex (FhcABCD) from Methylorubrum extorquens in complex with methylofuran
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I, M (A, E, I, M) | Formylmethanofuran dehydrogenase subunit A | polymer | 548 | 58563.0 | 4 | UniProt (A9W3R9) | Methylobacterium extorquens (strain PA1) | |
| 2 | B, F, J, N (B, F, J, N) | Tungsten-containing formylmethanofuran dehydrogenase, subunit B | polymer | 361 | 37032.5 | 4 | UniProt (A9W3S0) | Methylobacterium extorquens (strain PA1) | |
| 3 | C, G, K, O (C, G, K, O) | Formylmethanofuran dehydrogenase subunit C | polymer | 276 | 27896.6 | 4 | UniProt (A9W3R7) | Methylobacterium extorquens (strain PA1) | |
| 4 | D, H, L, P (D, H, L, P) | Formylmethanofuran--tetrahydromethanopterin formyltransferase | polymer | 310 | 32280.0 | 4 | UniProt (A9W3R8) | Methylobacterium extorquens (strain PA1) | H4MPT formyltransferase |
| 5 | AB, Q, QA (J, A, I) | FORMIC ACID | non-polymer | 46.0 | 3 | Chemie (FMT) | |||
| 6 | R (A) | N-[4,5,7-TRICARBOXYHEPTANOYL]-L-GAMMA-GLUTAMYL-N-{2-[4-({5-[(FORMYLAMINO)METHYL]-3-FURYL}METHOXY)PHENYL]ETHYL}-D-GLUTAMINE | non-polymer | 776.7 | 1 | Chemie (MFN) | |||
| 7 | OA, S (H, A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 8 | MA, NA, NB, OB, T... (E, M, A, I) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 9 | CA, HB, IB, V, W... (B, L, A) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 10 | CB, JA, JB, PA, SB... (J, D, L, H, P...) | POTASSIUM ION | non-polymer | 39.1 | 9 | Chemie (K) | |||
| 11 | AA, BA, DB, FA, WA (A, J, C, I) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 12 | DA, FB, GA, KA, LB... (B, K, C, D, L...) | D-GLUTAMIC ACID | non-polymer | 147.1 | 10 | Chemie (DGL) | |||
| 13 | EA (B) | AMINO GROUP | non-polymer | 16.0 | 1 | Chemie (NH2) | |||
| 14 | EB, GB, HA, IA, KB... (J, K, C, L, O...) | GLUTAMIC ACID | non-polymer | 147.1 | 8 | Chemie (GLU) | |||
| 15 | LA, VB (D, P) | BETA-L-ASPARTIC ACID | non-polymer | 133.1 | 2 | Chemie (IAS) | |||
| 16 | RA (I) | (2~{S})-3-[4-[[5-(aminomethyl)furan-3-yl]methoxy]phenyl]-2-(methylamino)propanoic acid | non-polymer | 304.3 | 1 | Chemie (L6K) | |||
| 17 | SA (I) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 18 | BB (J) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) |
Sequence modifications
C, G, K, O: 2 - 265 (UniProt: A9W3R7)
| PDB | External Database | Details |
|---|---|---|
| His 266 | - | expression tag |
| Gly 267 | - | expression tag |
| Ser 268 | - | expression tag |
| Ala 269 | - | expression tag |
| Trp 270 | - | expression tag |
| Ser 271 | - | expression tag |
| His 272 | - | expression tag |
| Pro 273 | - | expression tag |
| Gln 274 | - | expression tag |
| Phe 275 | - | expression tag |
| Glu 276 | - | expression tag |
| Lys 277 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 623088.6 | |
| Non-Polymers* | Number of molecules | 58 |
| Total formula weight | 5711.8 | |
| All* | Total formula weight | 628800.4 |
