6S08
Crystal Structure of Properdin (TSR domains N1 & 456)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Properdin | polymer | 225 | 25058.5 | 1 | UniProt (P27918) Pfam (PF00090) Pfam (PF22195) | Homo sapiens (Human) | Complement factor P |
| 2 | B (B) | Properdin | polymer | 110 | 11891.4 | 1 | UniProt (P27918) Pfam (PF18487) Pfam (PF00090) | Homo sapiens (Human) | Complement factor P |
| 3 | C (C) | beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose | branched | 326.3 | 1 | In PDB GlyTouCan (G36855WW) | |||
| 4 | D, E, F, G, H... (A, B) | alpha-D-mannopyranose | non-polymer | 180.2 | 8 | Chemie (MAN) | |||
| 5 | J (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | L (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | N (B) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 8 | O, P (A, B) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A: 256 - 469 (UniProt: P27918)
B: 26 - 132 (UniProt: P27918)
| PDB | External Database | Details |
|---|---|---|
| Gly 254 | - | expression tag |
| Ser 255 | - | expression tag |
| Ala 470 | - | expression tag |
| Ala 471 | - | expression tag |
| Ala 472 | - | expression tag |
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
| His 477 | - | expression tag |
| His 478 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 133 | - | expression tag |
| Ala 134 | - | expression tag |
| Ala 135 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36949.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 326.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1778.6 | |
| All* | Total formula weight | 39054.7 |
