6S08

Crystal Structure of Properdin (TSR domains N1 & 456)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Properdin	polymer	225	25058.5	1	UniProt (P27918) Pfam (PF00090) Pfam (PF22195) In PDB	Homo sapiens (Human)	Complement factor P
2	B	Properdin	polymer	110	11891.4	1	UniProt (P27918) Pfam (PF18487) Pfam (PF00090) In PDB	Homo sapiens (Human)	Complement factor P
3	C	beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose	branched		326.3	1	In PDB GlyTouCan (G36855WW)
4	A, B	alpha-D-mannopyranose	non-polymer		180.2	8	Chemie (MAN)
5	A	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
6	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7	B	alpha-L-fucopyranose	non-polymer		164.2	1	Chemie (FUC)
8		water	water		18.0	116	Chemie (HOH)

Sequence modifications

A: 256 - 469 (UniProt: P27918)

PDB	External Database	Details
Gly 254	-	expression tag
Ser 255	-	expression tag
Ala 470	-	expression tag
Ala 471	-	expression tag
Ala 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag
His 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag

B: 26 - 132 (UniProt: P27918)

PDB	External Database	Details
Ala 133	-	expression tag
Ala 134	-	expression tag
Ala 135	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36949.8
Branched	Number of molecules	1
	Total formula weight	326.3
Non-Polymers*	Number of molecules	11
	Total formula weight	1778.6
All*	Total formula weight	39054.7

*Water molecules are not included.