6RX3
Crystal structure of human syncytin 2 in post-fusion conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Syncytin-2 | polymer | 108 | 12196.8 | 3 | UniProt (P60508) Pfam (PF00429) | Homo sapiens (Human) | Endogenous retrovirus group FRD member 1,Envelope polyprotein,HERV-FRD,HERV-FRD_6p24.1 provirus ancestral Env polyprotein |
| 2 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | E, F, G (A, B, C) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A, B, C: 375 - 468 (UniProt: P60508)
| PDB | External Database | Details |
|---|---|---|
| Met 361 | - | initiating methionine |
| His 362 | - | expression tag |
| His 363 | - | expression tag |
| His 364 | - | expression tag |
| His 365 | - | expression tag |
| His 366 | - | expression tag |
| His 367 | - | expression tag |
| Glu 368 | - | expression tag |
| Asn 369 | - | expression tag |
| Leu 370 | - | expression tag |
| Tyr 371 | - | expression tag |
| Phe 372 | - | expression tag |
| Gln 373 | - | expression tag |
| Ser 374 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 36590.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 36625.8 |
