6RX3

Crystal structure of human syncytin 2 in post-fusion conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Syncytin-2	polymer	108	12196.8	3	UniProt (P60508) Pfam (PF00429) In PDB	Homo sapiens (Human)	Endogenous retrovirus group FRD member 1,Envelope polyprotein,HERV-FRD,HERV-FRD_6p24.1 provirus ancestral Env polyprotein
2	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
3		water	water		18.0	116	Chemie (HOH)

Sequence modifications

A, B, C: 375 - 468 (UniProt: P60508)

PDB	External Database	Details
Met 361	-	initiating methionine
His 362	-	expression tag
His 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
Glu 368	-	expression tag
Asn 369	-	expression tag
Leu 370	-	expression tag
Tyr 371	-	expression tag
Phe 372	-	expression tag
Gln 373	-	expression tag
Ser 374	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	36590.4
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	36625.8

*Water molecules are not included.