6RV2
Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Potassium channel subfamily K member 3 | polymer | 264 | 30117.0 | 4 | UniProt (O14649) Pfam (PF07885) In PDB | Homo sapiens (Human) | Acid-sensitive potassium channel protein TASK-1,TWIK-related acid-sensitive K(+) channel 1,Two pore potassium channel KT3.1,Two pore K(+) channel KT3.1 |
| 2 | A, C | POTASSIUM ION | non-polymer | 39.1 | 8 | Chemie (K) | |||
| 3 | A, B, C, D | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 7 | Chemie (Y01) | |||
| 4 | A, B, C | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 3 | Chemie (DMU) | |||
| 5 | A, B, D | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 4 | Chemie (PC1) | |||
| 6 | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 259 (UniProt: O14649)
| PDB | External Database | Details |
|---|---|---|
| Asn 260 | - | expression tag |
| Leu 261 | - | expression tag |
| Tyr 262 | - | expression tag |
| Phe 263 | - | expression tag |
| Gln 264 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 120468.1 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 8328.1 | |
| All* | Total formula weight | 128796.2 |
