6RUS

Structure of a functional properdin monomer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Properdin	polymer	234	25494.7	1	UniProt (P27918) Pfam (PF18487) Pfam (PF00090)	Homo sapiens (Human)	Complement factor P
2	B (B)	Properdin	polymer	221	24724.1	1	UniProt (P27918) Pfam (PF00090) Pfam (PF22195)	Homo sapiens (Human)	Complement factor P
3	C, D, E, F (C, D, E, F)	beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose	branched		326.3	4	In PDB GlyTouCan (G36855WW)
4	G (G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
5	H, I, J, K, L... (A, B)	alpha-D-mannopyranose	non-polymer		180.2	15	Chemie (MAN)
6	P, Q (A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)

Sequence modifications

A: 28 - 255 (UniProt: P27918)

PDB	External Database	Details
Glu 256	-	expression tag
Asn 257	-	expression tag
Leu 258	-	expression tag
Tyr 259	-	expression tag
Phe 260	-	expression tag
Gln 261	-	expression tag

B: 256 - 469 (UniProt: P27918)

PDB	External Database	Details
Gly 255	-	expression tag
Glu 470	-	expression tag
Asn 471	-	expression tag
Leu 472	-	expression tag
Tyr 473	-	expression tag
Phe 474	-	expression tag
Gln 475	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50218.9
Branched	Number of molecules	5
	Total formula weight	1875.7
Non-Polymers*	Number of molecules	17
	Total formula weight	2894.5
All*	Total formula weight	54989.1

*Water molecules are not included.