6RU8
Crystal structure of Casein Kinase I delta (CK1d) in complex with triple phosphorylated p63 PAD3P peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Casein kinase I isoform delta | polymer | 296 | 34424.8 | 4 | UniProt (P48730) Pfam (PF00069) | Homo sapiens (Human) | CKId,Tau-protein kinase CSNK1D |
| 2 | E, F, G, H (E, F, G, H) | Tumor protein 63 | polymer | 12 | 1371.1 | 4 | UniProt (Q9H3D4) | Homo sapiens | p63,Chronic ulcerative stomatitis protein,CUSP,Keratinocyte transcription factor KET,Transformation-related protein 63,TP63,Tumor protein p73-like,p73L,p40,p51 |
| 3 | FA, I, Q, Y (D, A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 4 | AA, BA, CA, DA, EA... (C, D, A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) | |||
| 5 | O, V (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | P, W, X (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | JA, KA, LA, MA, NA... (A, B, C, D, E...) | water | water | 18.0 | 525 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 294 (UniProt: P48730)
E, F, G, H: 582 - 593 (UniProt: Q9H3D4)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Tyr 593 | Glu 632 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 143183.6 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 3160.2 | |
| All* | Total formula weight | 146343.8 |
