6RTY
Crystal structure of the Patched ectodomain in complex with nanobody NB64
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein patched homolog 1 | polymer | 297 | 34138.8 | 1 | UniProt (Q13635) | Homo sapiens (Human) | PTC1 |
| 2 | B (B) | Llama-derived nanobody NB64 | polymer | 130 | 14043.6 | 1 | Lama glama | ||
| 3 | C, D, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A: 136 - 423 (UniProt: Q13635)
| PDB | External Database | Details |
|---|---|---|
| Glu 136 | Val 136 | conflict |
| Thr 137 | Ser 137 | conflict |
| Gly 138 | Arg 138 | conflict |
| Gly 424 | - | expression tag |
| Thr 425 | - | expression tag |
| Lys 426 | - | expression tag |
| His 427 | - | expression tag |
| His 428 | - | expression tag |
| His 429 | - | expression tag |
| His 430 | - | expression tag |
| His 431 | - | expression tag |
| His 432 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48182.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 48845.9 |
