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6RT8

Structure of catharanthine synthase - an alpha-beta hydrolase from Catharanthus roseus with a cleaviminium intermediate bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Catharanthine synthasepolymer33037077.08UniProt (A0A2P1GIW2)
Pfam (PF07859)
Catharanthus roseus (Madagascar periwinkle)Hydrolase 1,CrHL1
2I, K, L, N, O...
(A, B, C, D, E...)
18-carboxymethoxy-cleaviminiumnon-polymer337.48Chemie (KJE)
3J, M, P, T
(A, C, E, H)
HEXAETHYLENE GLYCOLnon-polymer282.34Chemie (P6G)
4AA, BA, U, V, W...
(G, H, A, B, C...)
waterwater18.0388Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 6 - 329 (UniProt: A0A2P1GIW2)
PDBExternal DatabaseDetails
Gly 0-expression tag
Pro 1-expression tag
Ala 2-expression tag
Ser 3-expression tag
Gln 4-expression tag
Thr 5-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight296615.7
Non-Polymers*Number of molecules12
Total formula weight3828.8
All*Total formula weight300444.5
*Water molecules are not included.

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PDB entries from 2025-04-23

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