6ROY
Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based inhibitory motif
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 104 | 11790.3 | 2 | UniProt (Q06124) Pfam (PF00017) | Homo sapiens (Human) | Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,Shp2,SH-PTP3 |
| 2 | B, D (D, C) | immune receptor tyrosine-based inhibitory motif (ITIM) | polymer | 11 | 1399.4 | 2 | UniProt (by SIFTS) (Q15116) | synthetic construct | |
| 3 | E, F, G, H (A, D, B, C) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 104 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 26379.3 | |
| All* | Total formula weight | 26379.3 |
