6RLB
Structure of the dynein-2 complex; tail domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | O6-alkylguanine-DNA alkyltransferase mutant,DYNC2H1 variant protein | polymer | 4513 | 515223.0 | 2 | UniProt (E5BBQ0) UniProt (B0I1S0) Pfam (PF02870) Pfam (PF12781) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199) Pfam (PF01035) Pfam (PF08385) Pfam (PF08393) Pfam (PF12774) Pfam (PF21264) Pfam (PF12775) Pfam (PF12780) Pfam (PF12777) In PDB | Homo sapiens (Human) | |
| 2 | C | WD repeat-containing protein 60 | polymer | 1066 | 122865.2 | 1 | UniProt (Q8WVS4) In PDB | Homo sapiens (Human) | |
| 3 | D | WD repeat-containing protein 34 | polymer | 564 | 60768.3 | 1 | UniProt (Q96EX3) Pfam (PF00400) In PDB | Homo sapiens (Human) | |
| 4 | E, F | Cytoplasmic dynein 2 light intermediate chain 1 | polymer | 351 | 39681.6 | 2 | UniProt (Q8TCX1) Pfam (PF05783) In PDB | Homo sapiens (Human) | Dynein 2 light intermediate chain |
| 5 | G, H | Dynein light chain roadblock-type 1 | polymer | 96 | 10934.6 | 2 | UniProt (Q9NP97) Pfam (PF03259) In PDB | Homo sapiens (Human) | Bithoraxoid-like protein,BLP,Dynein light chain 2A,cytoplasmic,Dynein-associated protein Km23,Roadblock domain-containing protein 1 |
| 6 | I, J, K, L, M... | Dynein light chain 1, cytoplasmic | polymer | 89 | 10381.9 | 6 | UniProt (P63167) Pfam (PF01221) In PDB | Homo sapiens (Human) | 8 kDa dynein light chain,DLC8,Dynein light chain LC8-type 1,Protein inhibitor of neuronal nitric oxide synthase,PIN |
Sequence modifications
A, B: -204 - -28 (UniProt: E5BBQ0)
A, B: 2 - 4307 (UniProt: B0I1S0)
C: 1 - 1066 (UniProt: Q8WVS4)
D: 1 - 536 (UniProt: Q96EX3)
| PDB | External Database | Details |
|---|---|---|
| Gly -205 | - | expression tag |
| Arg -176 | Glu 33 | conflict |
| Pro -27 | - | linker |
| Gly -26 | - | linker |
| Leu -25 | - | linker |
| Gly -24 | - | linker |
| Gly -23 | - | linker |
| Ser -22 | - | linker |
| Leu -21 | - | linker |
| Glu -20 | - | linker |
| Val -19 | - | linker |
| Leu -18 | - | linker |
| Phe -17 | - | linker |
| Gln -16 | - | linker |
| Gly -15 | - | linker |
| Pro -14 | - | linker |
| Asp -13 | - | linker |
| Tyr -12 | - | linker |
| Asp -11 | - | linker |
| Ile -10 | - | linker |
| Pro -9 | - | linker |
| Thr -8 | - | linker |
| Thr -7 | - | linker |
| Leu -6 | - | linker |
| Glu -5 | - | linker |
| Val -4 | - | linker |
| Leu -3 | - | linker |
| Phe -2 | - | linker |
| Gln -1 | - | linker |
| Gly 0 | - | linker |
| Pro 1 | - | linker |
C: 1 - 1066 (UniProt: Q8WVS4)
| PDB | External Database | Details |
|---|---|---|
| Lys 225 | Asn 225 | conflict |
| Phe 292 | Ser 292 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Trp 537 | - | expression tag |
| Ser 538 | - | expression tag |
| His 539 | - | expression tag |
| Pro 540 | - | expression tag |
| Gln 541 | - | expression tag |
| Phe 542 | - | expression tag |
| Glu 543 | - | expression tag |
| Lys 544 | - | expression tag |
| Gly 545 | - | expression tag |
| Ser 546 | - | expression tag |
| Ala 547 | - | expression tag |
| Gly 548 | - | expression tag |
| Ser 549 | - | expression tag |
| Ala 550 | - | expression tag |
| Ala 551 | - | expression tag |
| Gly 552 | - | expression tag |
| Ser 553 | - | expression tag |
| Gly 554 | - | expression tag |
| Ala 555 | - | expression tag |
| Gly 556 | - | expression tag |
| Trp 557 | - | expression tag |
| Ser 558 | - | expression tag |
| His 559 | - | expression tag |
| Pro 560 | - | expression tag |
| Gln 561 | - | expression tag |
| Phe 562 | - | expression tag |
| Glu 563 | - | expression tag |
| Lys 564 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 1377603.3 | |
| All* | Total formula weight | 1377603.3 |
