6RLA

Structure of the dynein-2 complex; motor domains

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	O6-alkylguanine-DNA alkyltransferase mutant,DYNC2H1 variant protein	polymer	4513	515223.0	2	UniProt (E5BBQ0) UniProt (B0I1S0) Pfam (PF02870) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199) Pfam (PF01035) Pfam (PF08385) Pfam (PF08393) Pfam (PF12774) Pfam (PF21264) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780)	Homo sapiens (Human)
2	C, F, G, H, K... (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	6	Chemie (ADP)
3	D, I (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
4	E, J (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

A, B: -204 - -28 (UniProt: E5BBQ0)

PDB	External Database	Details
Gly -205	-	expression tag
Arg -176	Glu 33	conflict
Pro -27	-	linker
Gly -26	-	linker
Leu -25	-	linker
Gly -24	-	linker
Gly -23	-	linker
Ser -22	-	linker
Leu -21	-	linker
Glu -20	-	linker
Val -19	-	linker
Leu -18	-	linker
Phe -17	-	linker
Gln -16	-	linker
Gly -15	-	linker
Pro -14	-	linker
Asp -13	-	linker
Tyr -12	-	linker
Asp -11	-	linker
Ile -10	-	linker
Pro -9	-	linker
Thr -8	-	linker
Thr -7	-	linker
Leu -6	-	linker
Glu -5	-	linker
Val -4	-	linker
Leu -3	-	linker
Phe -2	-	linker
Gln -1	-	linker
Gly 0	-	linker
Pro 1	-	linker

A, B: 2 - 4307 (UniProt: B0I1S0)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	1030446.1
Non-Polymers*	Number of molecules	10
	Total formula weight	3626.2
All*	Total formula weight	1034072.2

*Water molecules are not included.