6RJP

Bfl-1 in complex with alpha helical peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bcl-2-related protein A1	polymer	171	19718.3	2	UniProt (Q16548) Pfam (PF00452)	Homo sapiens (Human)	Bcl-2-like protein 5,Bcl2-L-5,Hemopoietic-specific early response protein,Protein BFL-1,Protein GRS
2	C, D (C, D)	Bcl-2-like protein 11	polymer	17	1895.1	2	UniProt (O43521) Pfam (PF08945)	Homo sapiens	Bcl2-L-11,Bcl2-interacting mediator of cell death
3	E, F, G (A, B, D)	water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, B: 1 - 149 (UniProt: Q16548)

PDB	External Database	Details
Met -21	-	initiating methionine
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

C, D: 1 - 17 (UniProt: O43521)

PDB	External Database	Details
Lv8 1	Trp 147	engineered mutation
Glu 4	Gln 150	conflict
Ala 5	Glu 151	conflict
Ala 12	Glu 158	conflict
Ala 16	Tyr 162	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	43226.8
All*	Total formula weight	43226.8

*Water molecules are not included.