6RJB
Human transketolase variant T382E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transketolase | polymer | 637 | 69675.5 | 2 | UniProt (P29401) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780) | Homo sapiens (Human) | TK |
| 2 | C, DA (A, B) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 2 | Chemie (TPP) | |||
| 3 | D, EA (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, FA (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | F, GA (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | AB, G, H, HA, I... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 40 | Chemie (EDO) | |||
| 7 | AA, BA (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 8 | BB, CA (B, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 9 | CB, DB (A, B) | water | water | 18.0 | 1165 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 623 (UniProt: P29401)
| PDB | External Database | Details |
|---|---|---|
| Glu 382 | Thr 382 | engineered mutation |
| Leu 624 | - | expression tag |
| Val 625 | - | expression tag |
| Pro 626 | - | expression tag |
| Arg 627 | - | expression tag |
| Gly 628 | - | expression tag |
| Ser 629 | - | expression tag |
| Leu 630 | - | expression tag |
| Glu 631 | - | expression tag |
| His 632 | - | expression tag |
| His 633 | - | expression tag |
| His 634 | - | expression tag |
| His 635 | - | expression tag |
| His 636 | - | expression tag |
| His 637 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 139351.0 | |
| Non-Polymers* | Number of molecules | 52 |
| Total formula weight | 3904.5 | |
| All* | Total formula weight | 143255.5 |
