6RH8
Revisiting pH-gated conformational switch. Complex HK853 mutant H260A -RR468 mutant D53A pH 5.3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Sensor histidine kinase | polymer | 258 | 29311.2 | 2 | UniProt (Q9WZV7) Pfam (PF00512) Pfam (PF02518) | Thermotoga maritima | |
| 2 | C, D (C, D) | Response regulator | polymer | 122 | 13804.2 | 2 | UniProt (Q9WYT9) Pfam (PF00072) | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) | |
| 3 | E, J (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | F, G, H, I, K... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 19 | Chemie (SO4) | |||
| 5 | AA, BA, CA, Z (B, C, D, A) | water | water | 18.0 | 488 | Chemie (HOH) |
Sequence modifications
A, B: 232 - 489 (UniProt: Q9WZV7)
C, D: 1 - 122 (UniProt: Q9WYT9)
| PDB | External Database | Details |
|---|---|---|
| Ala 260 | His 260 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 53 | Asp 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 86230.9 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2679.6 | |
| All* | Total formula weight | 88910.5 |
