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6RG4

Crystal structure of human Carbonic anhydrase II in complex with (R)-4-(2-benzyl-4-methylpiperazin-1-yl)benzenesulfonamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer26029289.11UniProt (P00918)
Pfam (PF00194)
Homo sapiens (Human)Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C, D
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
4E
(A)
4-[(3~{S})-4-methyl-3-(phenylmethyl)piperazin-1-yl]carbonylbenzenesulfonamidenon-polymer373.51Chemie (K45)
5F
(A)
waterwater18.0279Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29289.1
Non-Polymers*Number of molecules4
Total formula weight623.1
All*Total formula weight29912.1
*Water molecules are not included.

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PDB entries from 2026-01-14

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