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6RFQ

Cryo-EM structure of a respiratory complex I assembly intermediate with NDUFAF2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASubunit NUAM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer72879088.11UniProt (Q9UUU3)
Pfam (PF13510)
Pfam (PF10588)
Pfam (PF22117)
Pfam (PF22151)
Pfam (PF00384)
Pfam (PF09326)
UniProt (by SIFTS) (F2Z6F1)
In PDB		Yarrowia lipolytica (Candida lipolytica)
2BSubunit NUBM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer48853829.51UniProt (Q9UUU2)
Pfam (PF01512)
Pfam (PF22461)
Pfam (PF10589)
UniProt (by SIFTS) (F2Z660)
In PDB		Yarrowia lipolytica (Candida lipolytica)
3CSubunit NUCM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer46652494.91UniProt (Q9UUU1)
Pfam (PF00346)
UniProt (by SIFTS) (F2Z626)
In PDB		Yarrowia lipolytica (Candida lipolytica)
4DSubunit NIMM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer879806.21UniProt (A0A1D8NC63)
Pfam (PF15879)
UniProt (by SIFTS) (B5FVD3)
In PDB		Yarrowia lipolytica (Candida lipolytica)
5ESubunit NUEM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer37542765.71UniProt (A0A371BY45)
Pfam (PF01370)
UniProt (by SIFTS) (Q6C7X4)
In PDB		Yarrowia lipolytica
6FSubunit NUFM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer14416657.91UniProt (A0A371C5F3)
Pfam (PF04716)
UniProt (by SIFTS) (Q6C4W9)
In PDB		Yarrowia lipolytica
7GSubunit NUGM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer28132389.61UniProt (Q9UUU0)
Pfam (PF00329)
UniProt (by SIFTS) (F2Z6D7)
In PDB		Yarrowia lipolytica (Candida lipolytica)
8HSubunit NUHM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer24327247.41UniProt (Q9UUT9)
Pfam (PF01257)
UniProt (by SIFTS) (F2Z6C0)
In PDB		Yarrowia lipolytica (Candida lipolytica)
9ISubunit NUIM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer22925682.31UniProt (Q9UUT8)
Pfam (PF12838)
UniProt (by SIFTS) (F2Z619)
In PDB		Yarrowia lipolytica (Candida lipolytica)
10JSubunit NUJM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer19820849.61UniProt (A0A371CB65)
UniProt (by SIFTS) (Q6C674)
In PDB		Yarrowia lipolytica
11KSubunit NUKM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer21023455.21UniProt (Q9UUT7)
Pfam (PF01058)
UniProt (by SIFTS) (Q6C2Q1)
In PDB		Yarrowia lipolytica (Candida lipolytica)
12LSubunit NULM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer899815.91UniProt (Q9B6D4)
Pfam (PF00420)
In PDB		Yarrowia lipolyticaNADH dehydrogenase subunit 4L, subunit ND4L
13OAcyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I)polymer10912053.61UniProt (A0A1H6PXT9)
Pfam (PF00550)
UniProt (by SIFTS) (Q6C926)
In PDB		Yarrowia lipolytica (Candida lipolytica)
14PSubunit NB4M of protein NADH:Ubiquinone Oxidoreductase (Complex I)polymer12414778.81UniProt (A0A1D8N3C8)
Pfam (PF13233)
UniProt (by SIFTS) (Q6CI60)
In PDB		Yarrowia lipolytica (Candida lipolytica)
15QAcyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I)polymer13214444.51UniProt (A0A1D8NG21)
Pfam (PF00550)
UniProt (by SIFTS) (Q6C7X2)
In PDB		Yarrowia lipolytica (Candida lipolytica)
16RSubunit NI2M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer10912902.91UniProt (A0A1D8NDL1)
UniProt (by SIFTS) (Q6C9Z1)
In PDB		Yarrowia lipolytica (Candida lipolytica)
17SSubunit NESM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer24928479.91UniProt (Q6ZY23)
UniProt (by SIFTS) (F2Z673)
In PDB		Yarrowia lipolytica
18USubunit NUPM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer17219355.21UniProt (A0A371C2D0)
Pfam (PF06747)
UniProt (by SIFTS) (Q6CGB4)
In PDB		Yarrowia lipolytica
19WSubunit NB6M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer12314112.41UniProt (A0A1H6PPE5)
Pfam (PF06212)
UniProt (by SIFTS) (B5FVF8)
In PDB		Yarrowia lipolytica (Candida lipolytica)
20XSubunit NUXM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer16918588.21UniProt (A0A1D8NKB4)
Pfam (PF10785)
Pfam (PF12853)
UniProt (by SIFTS) (Q6C4A6)
In PDB		Yarrowia lipolytica (Candida lipolytica)
21YSubunit NUYM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer16118656.11UniProt (A0A1D8N7X0)
Pfam (PF04800)
UniProt (by SIFTS) (Q6CEK9)
In PDB		Yarrowia lipolytica (Candida lipolytica)
22ZSubunit NUZM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer18219772.51UniProt (A0A1D8N3H5)
UniProt (by SIFTS) (Q6CI10)
In PDB		Yarrowia lipolytica
23aSubunit NIAM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer14917328.51UniProt (A0A1D8ND94)
Pfam (PF05821)
UniProt (by SIFTS) (Q6CA88)
In PDB		Yarrowia lipolytica
24bSubunit NEBM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer748059.41UniProt (A0A1D8NGI5)
In PDB		Yarrowia lipolytica
25cSubunit NB2M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer606948.91UniProt (A0A371C0F2)
Pfam (PF08122)
UniProt (by SIFTS) (B5FVE5)
In PDB		Yarrowia lipolytica
26dSubunit NIDM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer9211039.31UniProt (A0A1D8N596)
Pfam (PF10249)
UniProt (by SIFTS) (B5RSK3)
In PDB		Yarrowia lipolytica (Candida lipolytica)
27eSubunit NUVM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer677807.11UniProt (A0A1D8NFX6)
In PDB		Yarrowia lipolytica
28fSubunit NI8M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer879621.11UniProt (A0A1H6PJS3)
Pfam (PF05047)
UniProt (by SIFTS) (Q6CD73)
In PDB		Yarrowia lipolytica (Candida lipolytica)
29gSubunit NI9M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer788921.21UniProt (A0A1D8NJR0)
UniProt (by SIFTS) (B5FVF3)
In PDB		Yarrowia lipolytica
30iSubunit N7BM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer909794.01UniProt (A0A1H6Q311)
In PDB		Yarrowia lipolytica
31jSubunit NUUM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer9310494.91UniProt (Q6ZY24)
UniProt (by SIFTS) (B5RSK9)
In PDB		Yarrowia lipolytica (Candida lipolytica)
32kSubunit N7BML assembly factorpolymer23727647.51UniProt (A0A1D8NGE3)
Pfam (PF05071)
UniProt (by SIFTS) (Q6C7L6)
In PDB		Yarrowia lipolytica
33nSubunit NUNM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer12013523.11UniProt (A0A371CFV9)
UniProt (by SIFTS) (Q6C1R9)
In PDB		Yarrowia lipolytica
341Subunit NU1M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer34138361.31UniProt (S5U3V2)
Pfam (PF00146)
UniProt (by SIFTS) (Q9B6E8)
In PDB		Yarrowia lipolytica
352Subunit NU2M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer46953353.41UniProt (S5U4R9)
Pfam (PF00361)
UniProt (by SIFTS) (Q9B6C8)
In PDB		Yarrowia lipolytica
363Subunit NU3M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer12814478.31UniProt (S5TMS4)
Pfam (PF00507)
UniProt (by SIFTS) (Q9B6C7)
In PDB		Yarrowia lipolytica
374Subunit NU4M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer48654506.61UniProt (S5TMP9)
Pfam (PF00361)
UniProt (by SIFTS) (Q9B6D6)
In PDB		Yarrowia lipolytica
385Subunit NU5M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer65573740.71UniProt (S5TF58)
Pfam (PF00662)
Pfam (PF00361)
UniProt (by SIFTS) (Q9B6D3)
In PDB		Yarrowia lipolytica
396Subunit NU6M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer18520765.11UniProt (Q9B6E9)
Pfam (PF00499)
In PDB		Yarrowia lipolyticaNADH dehydrogenase subunit 6, Subunit ND6
408Subunit NB8M of NADH:Ubiquinone Oxidoreductase (Complex I)polymer9911219.01UniProt (A0A1H6PKH9)
Pfam (PF05676)
UniProt (by SIFTS) (B5FVG1)
In PDB		Yarrowia lipolytica (Candida lipolytica)
419Subunit NIPM of NADH:Ubiquinone Oxidoreductase (Complex I)polymer8910035.71UniProt (A0A1D8NNZ0)
Pfam (PF10200)
UniProt (by SIFTS) (B5RSL7)
In PDB		Yarrowia lipolytica (Candida lipolytica)
42K, A, B, IIRON/SULFUR CLUSTERnon-polymer351.66Chemie (SF4)
43A, HFE2/S2 (INORGANIC) CLUSTERnon-polymer175.82Chemie (FES)
44BFLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
45ENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
46J, g, 4, 5, I...1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINEnon-polymer748.110Chemie (3PE)
47J, jLauryl Maltose Neopentyl Glycolnon-polymer1005.22Chemie (LMN)
48J, X, g, 4CARDIOLIPINnon-polymer1464.04Chemie (CDL)
49O, QS-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioatenon-polymer568.72Chemie (ZMP)
50W, n, 5DIUNDECYL PHOSPHATIDYL CHOLINEnon-polymer622.84Chemie (PLC)
512, 4Phosphatidylinositolnon-polymer887.13Chemie (T7X)
5221-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer758.11Chemie (CPL)
Sequence modifications
g: 1 - 78 (UniProt: A0A1D8NJR0)
PDBExternal DatabaseDetails
Gly 71Gln 71conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains41
Total formula weight974871.2
Non-Polymers*Number of molecules36
Total formula weight26058.6
All*Total formula weight1000929.8
*Water molecules are not included.

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PDB entries from 2024-07-17

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