6RF8

Cryo-EM structure of the N-terminal DC repeat (NDC) of NDC-NDC chimera (human sequence) bound to 13-protofilament GDP-microtubule

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	N	Neuronal migration protein doublecortin	polymer	99	11441.8	1	UniProt (O43602) Pfam (PF03607) In PDB	Homo sapiens (Human)	Doublin,Lissencephalin-X,Lis-X
2	b, B	Tubulin beta-2B chain	polymer	429	48113.1	2	UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) In PDB	Bos taurus (Bovine)
3	A, a	Tubulin alpha-1B chain	polymer	432	48263.6	2	UniProt (P81947) Pfam (PF00091) Pfam (PF03953) In PDB	Bos taurus (Bovine)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
4	b, B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
5	A, a	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
6	A, a	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

b, B: 1 - 429 (UniProt: Q6B856)

PDB	External Database	Details
Ala 55	Thr 55	conflict
Val 170	Met 170	conflict
Ala 296	Ser 296	conflict
Val 316	Ile 316	conflict

A, a: 1 - 441 (UniProt: P81947)

PDB	External Database	Details
-	Ser 38	deletion
-	Asp 39	deletion
-	Lys 40	deletion
-	Thr 41	deletion
-	Ile 42	deletion
-	Gly 43	deletion
-	Gly 44	deletion
-	Gly 45	deletion
-	Asp 46	deletion

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	204195.3
Non-Polymers*	Number of molecules	6
	Total formula weight	1981.4
All*	Total formula weight	206176.7

*Water molecules are not included.