6RCX

Mycobacterial 4'-phosphopantetheinyl transferase PptAb in complex with the ACP domain of PpsC.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Possible 4'-phosphopantetheinyl transferase	polymer	232	25432.1	1	UniProt (B1MD73) Pfam (PF17837) Pfam (PF01648) In PDB	Mycobacteroides abscessus ATCC 19977
2	B	Phthiocerol synthesis polyketide synthase type I PpsC	polymer	157	16791.7	1	UniProt (P96202) Pfam (PF00550) In PDB	Mycobacterium abscessus ATCC 19977	Beta-ketoacyl-acyl-carrier-protein synthase I
3	A	COENZYME A	non-polymer		767.5	1	Chemie (COA)
4	A	MANGANESE (II) ION	non-polymer		54.9	3	Chemie (MN)
5	B	CACODYLATE ION	non-polymer		137.0	1	Chemie (CAC)
6		water	water		18.0	144	Chemie (HOH)

Sequence modifications

A: 1 - 219 (UniProt: B1MD73)

PDB	External Database	Details
Lys 220	-	expression tag
Leu 221	-	expression tag
Ala 222	-	expression tag
Ala 223	-	expression tag
Ala 224	-	expression tag
Leu 225	-	expression tag
Glu 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag

B: 2057 - 2188 (UniProt: P96202)

PDB	External Database	Details
Met 2036	-	initiating methionine
Gly 2037	-	expression tag
Ser 2038	-	expression tag
Ser 2039	-	expression tag
His 2040	-	expression tag
His 2041	-	expression tag
His 2042	-	expression tag
His 2043	-	expression tag
His 2044	-	expression tag
His 2045	-	expression tag
Ser 2046	-	expression tag
Ser 2047	-	expression tag
Gly 2048	-	expression tag
Leu 2049	-	expression tag
Val 2050	-	expression tag
Pro 2051	-	expression tag
Arg 2052	-	expression tag
Gly 2053	-	expression tag
Ser 2054	-	expression tag
His 2055	-	expression tag
Met 2056	-	expression tag
Ala 2105	Ser 2105	engineered mutation
Thr 2189	-	expression tag
Ser 2190	-	expression tag
Gly 2191	-	expression tag
Ser 2192	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	42223.7
Non-Polymers*	Number of molecules	5
	Total formula weight	1069.3
All*	Total formula weight	43293.0

*Water molecules are not included.