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6RCH

Crystal structure of Casein kinase I isoform delta (CK1 delta) complexed with SR4133 inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BCasein kinase I isoform deltapolymer29634424.82UniProt (P48730)
Pfam (PF00069)
In PDB
Homo sapiens (Human)CKId,Tau-protein kinase CSNK1D
2A, BSULFATE IONnon-polymer96.17Chemie (SO4)
3A, B1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
4A, BSODIUM IONnon-polymer23.02Chemie (NA)
5A~{N}-[[4,5-bis(fluoranyl)-1~{H}-benzimidazol-2-yl]methyl]-2-morpholin-4-yl-9-naphthalen-2-yl-purin-6-aminenon-polymer512.51Chemie (K0B)
6waterwater18.0776Chemie (HOH)
Sequence modifications
A, B: 1 - 294 (UniProt: P48730)
PDBExternal DatabaseDetails
Ser -1-expression tag
Met 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68849.6
Non-Polymers*Number of molecules16
Total formula weight1603.3
All*Total formula weight70453.0
*Water molecules are not included.

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PDB entries from 2024-06-12

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