6RCH
Crystal structure of Casein kinase I isoform delta (CK1 delta) complexed with SR4133 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Casein kinase I isoform delta | polymer | 296 | 34424.8 | 2 | UniProt (P48730) Pfam (PF00069) | Homo sapiens (Human) | CKId,Tau-protein kinase CSNK1D |
| 2 | C, D, E, M, N... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 3 | F, G, H, I, J... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | K, R (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | L (A) | ~{N}-[[4,5-bis(fluoranyl)-1~{H}-benzimidazol-2-yl]methyl]-2-morpholin-4-yl-9-naphthalen-2-yl-purin-6-amine | non-polymer | 512.5 | 1 | Chemie (K0B) | |||
| 6 | S, T (A, B) | water | water | 18.0 | 776 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 294 (UniProt: P48730)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68849.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1603.3 | |
| All* | Total formula weight | 70453.0 |
