6RA4
Human ARGONAUTE-2 PAZ DOMAIN (214-347) IN COMPLEX WITH CGUGACUCU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein argonaute-2 | polymer | 136 | 15817.4 | 2 | UniProt (Q9UKV8) Pfam (PF02170) | Homo sapiens (Human) | hAgo2,Argonaute RISC catalytic component 2,Eukaryotic translation initiation factor 2C 2,eIF2C 2,PAZ Piwi domain protein,PPD,Protein slicer |
| 2 | C, D (L, M) | RNA (5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3') | polymer | 9 | 2808.7 | 2 | Homo sapiens | ||
| 3 | E, F (L, M) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | G, H, I, J (A, B, L, M) | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A, B: 214 - 347 (UniProt: Q9UKV8)
| PDB | External Database | Details |
|---|---|---|
| Gly 212 | - | expression tag |
| Pro 213 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 37252.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 37436.5 |
