6R8X
COAGULATION FACTOR XI CATALYTIC DOMAIN IN COMPLEX WITH FAB-PORTION OF MAA868
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor XI | polymer | 238 | 26856.5 | 1 | UniProt (P03951) Pfam (PF00089) | Homo sapiens (human) | FXI,Plasma thromboplastin antecedent,PTA |
| 2 | B (B) | anti-Factor-XI Fab fragment light chain MAA868 | polymer | 216 | 22921.2 | 1 | unidentified | ||
| 3 | C (C) | anti-Factor-XI Fab fragment heavy chain MAA868 | polymer | 236 | 24963.9 | 1 | unidentified | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 413 | Chemie (HOH) |
Sequence modifications
A: 16 - 245 (UniProt: P03951)
| PDB | External Database | Details |
|---|---|---|
| Ser 123 | Cys 500 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74741.6 | |
| All* | Total formula weight | 74741.6 |
