6R8G
Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with 4-(3,4-difluorophenyl)thiazol-2-amine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Malate dehydrogenase | polymer | 324 | 35362.9 | 4 | UniProt (Q6VVP7) Pfam (PF00056) Pfam (PF02866) In PDB | Plasmodium falciparum | |
2 | A, C, D | 4-[3,4-bis(fluoranyl)phenyl]-1,3-thiazol-2-amine | non-polymer | 212.2 | 4 | Chemie (JUT) | |||
3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
4 | C | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
5 | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 313 (UniProt: Q6VVP7)
PDB | External Database | Details |
---|---|---|
Ala 314 | - | expression tag |
Ala 315 | - | expression tag |
Ala 316 | - | expression tag |
Leu 317 | - | expression tag |
Glu 318 | - | expression tag |
His 319 | - | expression tag |
His 320 | - | expression tag |
His 321 | - | expression tag |
His 322 | - | expression tag |
His 323 | - | expression tag |
His 324 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 141451.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1535.3 | |
All* | Total formula weight | 142987.0 |