6R51
Crystal structure of apo PPEP-1(E143A/Y178F) in complex with fibrinogen-derived substrate peptide Ac-SLRPAPP-CONH2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D (B, A, C) | Pro-Pro endopeptidase | polymer | 198 | 21909.6 | 3 | UniProt (Q183R7) Pfam (PF07737) | Peptoclostridium difficile | PPEP-1,Zinc metalloprotease Zmp1 |
| 2 | B, E, F (E, D, F) | ACE-SER-LEU-ARG-PRO-ALA-PRO-LPD | polymer | 8 | 762.9 | 3 | Homo sapiens | ||
| 3 | G (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 4 | H, I, J, K, L... (B, E, A, C, D...) | water | water | 18.0 | 432 | Chemie (HOH) |
Sequence modifications
B, A, C: 27 - 220 (UniProt: Q183R7)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
| His 25 | - | expression tag |
| Met 26 | - | expression tag |
| Ala 143 | Glu 143 | conflict |
| Phe 178 | Tyr 178 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 68017.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 68112.7 |
