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6R3V

Crystal Structure of RhoA-GDP-Pi in Complex with RhoGAP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Rho GTPase-activating protein 1polymer43950495.51UniProt (Q07960)
Pfam (PF13716)
Pfam (PF00620)
Homo sapiens (Human)CDC42 GTPase-activating protein,GTPase-activating protein rhoGAP,Rho-related small GTPase protein activator,Rho-type GTPase-activating protein 1,p50-RhoGAP
2B
(B)
Transforming protein RhoApolymer19321799.21UniProt (P61586)
Pfam (PF00071)
Homo sapiens (Human)Rho cDNA clone 12,h12
3C, G
(A, B)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
4D
(B)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.21Chemie (MES)
5E
(B)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
6F
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7H
(B)
2,3-DIHYDROXY-1,4-DITHIOBUTANEnon-polymer154.31Chemie (DTT)
8I, J
(A, B)
waterwater18.0254Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight72294.7
Non-Polymers*Number of molecules6
Total formula weight1006.9
All*Total formula weight73301.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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