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6R1A

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 20b

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Cereblon isoform 4polymer12513703.63UniProt (A4TVL0)Magnetospirillum gryphiswaldense MSR-1
2D, G, K
(A, B, C)
ZINC IONnon-polymer65.43Chemie (ZN)
3E, H
(A, B)
S-Thalidomidenon-polymer258.22Chemie (EF2)
4F, I, J, M
(A, B, C)
PHOSPHATE IONnon-polymer95.04Chemie (PO4)
5L
(C)
[(2~{R})-pyrrolidin-2-yl]methyl ~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamatenon-polymer255.31Chemie (JP8)
6N, O, P
(A, B, C)
waterwater18.0232Chemie (HOH)
Sequence modifications
A, B, C: 1 - 124 (UniProt: A4TVL0)
PDBExternal DatabaseDetails
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight41110.7
Non-Polymers*Number of molecules10
Total formula weight1347.8
All*Total formula weight42458.6
*Water molecules are not included.

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PDB entries from 2025-07-02

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