6R12
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Cereblon isoform 4 | polymer | 125 | 13703.6 | 3 | UniProt (A4TVL0) | Magnetospirillum gryphiswaldense MSR-1 | |
| 2 | D (F) | Cereblon isoform 4 | polymer | 5 | 443.5 | 1 | Magnetospirillum gryphiswaldense MSR-1 | ||
| 3 | E, H, M (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F, N (A, C) | S-Thalidomide | non-polymer | 258.2 | 2 | Chemie (EF2) | |||
| 5 | G, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 6 | I (B) | ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-2-phenyl-ethanamide | non-polymer | 232.2 | 1 | Chemie (JOT) | |||
| 7 | K, L (B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | O, P, Q, R (A, B, C, F) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 124 (UniProt: A4TVL0)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 41554.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1205.8 | |
| All* | Total formula weight | 42760.0 |
