6QZR
14-3-3 sigma in complex with FOXO1 pT24 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | 14-3-3 protein sigma | polymer | 253 | 28226.5 | 8 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | R, J, M, N, O... | Forkhead box protein O1 | polymer | 11 | 1451.6 | 8 | UniProt (Q12778) In PDB | Homo sapiens | Forkhead box protein O1A,Forkhead in rhabdomyosarcoma |
| 3 | A, B, F, H | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 4 | Chemie (B3P) | |||
| 4 | G, A, D, H | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 680 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, H, G: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 237425.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1774.0 | |
| All* | Total formula weight | 239199.0 |
