6QVE

NgCKK (Naegleria Gruberi CKK) decorated 14pf taxol-GDP microtubule

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (C, A)	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (P68363) Pfam (PF00091) Pfam (PF03953)	Homo sapiens (Human)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2	C (W)	Predicted protein	polymer	187	20879.1	1	UniProt (D2VJG4) Pfam (PF08683)	Naegleria gruberi (Amoeba)
3	D, E (H, G)	Beta1-tubulin	polymer	444	49717.6	2	UniProt (A0A2K5HGL3) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P07437)	Homo sapiens (Human)
4	F, H (C, A)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
5	G, I (C, A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	J, L (H, G)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
7	K, M (H, G)	TAXOL	non-polymer		853.9	2	Chemie (TA1)

Sequence modifications

W: 621 - 788 (UniProt: D2VJG4)

PDB	External Database	Details
Met 602	-	initiating methionine
Ala 603	-	expression tag
His 604	-	expression tag
His 605	-	expression tag
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
Ser 610	-	expression tag
Ala 611	-	expression tag
Ala 612	-	expression tag
Leu 613	-	expression tag
Glu 614	-	expression tag
Val 615	-	expression tag
Leu 616	-	expression tag
Phe 617	-	expression tag
Gln 618	-	expression tag
Gly 619	-	expression tag
Pro 620	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	220723.2
Non-Polymers*	Number of molecules	8
	Total formula weight	3689.2
All*	Total formula weight	224412.4

*Water molecules are not included.