6QVE
NgCKK (Naegleria Gruberi CKK) decorated 14pf taxol-GDP microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, A) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (P68363) Pfam (PF00091) Pfam (PF03953) | Homo sapiens (Human) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | C (W) | Predicted protein | polymer | 187 | 20879.1 | 1 | UniProt (D2VJG4) Pfam (PF08683) | Naegleria gruberi (Amoeba) | |
| 3 | D, E (H, G) | Beta1-tubulin | polymer | 444 | 49717.6 | 2 | UniProt (A0A2K5HGL3) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P07437) | Homo sapiens (Human) | |
| 4 | F, H (C, A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | G, I (C, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | J, L (H, G) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 7 | K, M (H, G) | TAXOL | non-polymer | 853.9 | 2 | Chemie (TA1) PubChem (16757828) PubChem (16760674) PubChem (21458255) PubChem (23307219) PubChem (23412627) PubChem (23636632) PubChem (24848897) PubChem (24867246) PubChem (16760177) PubChem (16742549) PubChem (21733096) PubChem (23307242) PubChem (23307253) PubChem (23307913) PubChem (24754091) PubChem (24207713) PubChem (24791027) PubChem (25200067) PubChem (42613129) PubChem (42620039) PubChem (44155032) PubChem (44276363) PubChem (44279927) PubChem (44335735) PubChem (44291178) PubChem (44328863) PubChem (44342632) PubChem (44356895) PubChem (44378736) PubChem (45489039) PubChem (46782671) PubChem (71209844) PubChem (53313247) PubChem (53298534) PubChem (54259297) PubChem (54259299) PubChem (57489669) PubChem (57999380) PubChem (58460861) PubChem (58777027) PubChem (58798493) PubChem (58596717) PubChem (59048611) PubChem (59042813) PubChem (58877402) PubChem (44323108) PubChem (44356961) PubChem (44403716) PubChem (60005248) PubChem (59873251) PubChem (59914794) PubChem (59919147) PubChem (60123436) PubChem (60011010) PubChem (60147315) PubChem (66795656) PubChem (14060298) PubChem (46781469) PubChem (176586897) PubChem (177678861) PubChem (36314) PubChem (60915) PubChem (177409) PubChem (184492) PubChem (70801836) PubChem (70842048) PubChem (70848451) PubChem (70856170) PubChem (441276) PubChem (73707502) PubChem (73759704) PubChem (89493063) PubChem (89847578) PubChem (90057663) PubChem (91122402) PubChem (91885464) PubChem (49868078) PubChem (5317123) PubChem (5321715) PubChem (101920282) PubChem (5352019) PubChem (121459571) PubChem (122361554) PubChem (6604028) PubChem (6604616) PubChem (6604814) PubChem (6713921) PubChem (6915727) PubChem (124747272) PubChem (124893098) PubChem (9875988) PubChem (54259298) PubChem (126968948) PubChem (129395998) PubChem (129627423) PubChem (10748131) PubChem (132517454) PubChem (11320430) PubChem (11354895) PubChem (134368714) PubChem (134972678) PubChem (137705323) PubChem (138106885) PubChem (140731501) PubChem (140512017) PubChem (146034004) PubChem (153289350) PubChem (154037993) PubChem (57908851) PubChem (57946364) PubChem (155982214) PubChem (159121804) PubChem (160053861) PubChem (159716711) PubChem (160171678) PubChem (160585530) PubChem (163077211) PubChem (163077212) PubChem (163077209) PubChem (163284947) PubChem (58803237) PubChem (168322423) PubChem (169917882) PubChem (171036874) PubChem (175758871) PubChem (59844545) PubChem (59904698) PubChem (60123443) PubChem (70943371) PubChem (71096818) PubChem (73759783) PubChem (101598423) PubChem (118528174) PubChem (4666) PubChem (124747271) PubChem (124747273) PubChem (124747274) PubChem (5460441) PubChem (126761000) PubChem (9854162) PubChem (9897470) PubChem (10033513) PubChem (10485732) PubChem (11506104) PubChem (11828953) PubChem (14060299) PubChem (14060304) PubChem (14060306) PubChem (14060309) PubChem (15983941) PubChem (133052515) PubChem (133640187) PubChem (134715514) PubChem (143890766) PubChem (152743329) PubChem (154828192) PubChem (144453087) PubChem (160585532) PubChem (163077210) PubChem (163077213) PubChem (163077214) PubChem (163077215) PubChem (165084161) PubChem (166711459) PubChem (167423928) PubChem (170014955) PubChem (170362150) |
Sequence modifications
W: 621 - 788 (UniProt: D2VJG4)
| PDB | External Database | Details |
|---|---|---|
| Met 602 | - | initiating methionine |
| Ala 603 | - | expression tag |
| His 604 | - | expression tag |
| His 605 | - | expression tag |
| His 606 | - | expression tag |
| His 607 | - | expression tag |
| His 608 | - | expression tag |
| His 609 | - | expression tag |
| Ser 610 | - | expression tag |
| Ala 611 | - | expression tag |
| Ala 612 | - | expression tag |
| Leu 613 | - | expression tag |
| Glu 614 | - | expression tag |
| Val 615 | - | expression tag |
| Leu 616 | - | expression tag |
| Phe 617 | - | expression tag |
| Gln 618 | - | expression tag |
| Gly 619 | - | expression tag |
| Pro 620 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 220723.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3689.2 | |
| All* | Total formula weight | 224412.4 |
