6QSX
Complement factor B protease domain in complex with the reversible inhibitor ((2S,4S)-1-((5,7-dimethyl-1H-indol-4-yl)methyl)-4-methoxypiperidin-2-yl)methanol.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Complement factor B | polymer | 291 | 32955.9 | 2 | UniProt (P00751) Pfam (PF00089) | Homo sapiens (Human) | C3/C5 convertase,Glycine-rich beta glycoprotein,GBG,PBF2,Properdin factor B |
| 2 | C, D, E, G, H... (AAA, BBB) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 3 | F, K (AAA, BBB) | [(2~{S},4~{S})-1-[(5,7-dimethyl-1~{H}-indol-4-yl)methyl]-4-methoxy-piperidin-2-yl]methanol | non-polymer | 302.4 | 2 | Chemie (JGN) | |||
| 4 | L, M (BBB) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | N, O (AAA, BBB) | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65911.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1408.1 | |
| All* | Total formula weight | 67319.8 |
