6QRA
Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | tRNA (guanine-N(1)-)-methyltransferase | polymer | 244 | 26434.7 | 2 | UniProt (B1MDI3) Pfam (PF01746) | Mycobacterium abscessus | M1G-methyltransferase,tRNA [GM37] methyltransferase |
| 2 | C, D (A, B) | 3-[1-[[4-(piperidin-1-ylmethyl)phenyl]methyl]indol-6-yl]-1~{H}-pyrazol-5-amine | non-polymer | 385.5 | 2 | Chemie (JDK) | |||
| 3 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 242 (UniProt: B1MDI3)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52869.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 867.1 | |
| All* | Total formula weight | 53736.4 |
