6QR2
Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | tRNA (guanine-N(1)-)-methyltransferase | polymer | 244 | 26434.7 | 2 | UniProt (B1MDI3) Pfam (PF01746) | Mycobacterium abscessus | M1G-methyltransferase,tRNA [GM37] methyltransferase |
| 2 | C, F (A, B) | 5-azanyl-3-[1-[(2-oxidanylpyridin-3-yl)methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile | non-polymer | 330.3 | 2 | Chemie (JQB) | |||
| 3 | D, E, G (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 242 (UniProt: B1MDI3)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52869.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 948.9 | |
| All* | Total formula weight | 53818.2 |
