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6QQV

Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BtRNA (guanine-N(1)-)-methyltransferasepolymer24426434.72UniProt (B1MDI3)
Pfam (PF01746)
In PDB
Mycobacterium abscessusM1G-methyltransferase,tRNA [GM37] methyltransferase
2A, B2-[[6-(5-azanyl-1~{H}-pyrazol-3-yl)indol-1-yl]methyl]benzenecarbonitrilenon-polymer313.42Chemie (JEW)
3BSULFATE IONnon-polymer96.12Chemie (SO4)
4waterwater18.0275Chemie (HOH)
Sequence modifications
A, B: 1 - 242 (UniProt: B1MDI3)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight52869.3
Non-Polymers*Number of molecules4
Total formula weight818.8
All*Total formula weight53688.2
*Water molecules are not included.

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PDB entries from 2024-08-28

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