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6QOK

Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 14 (Methyl 2-aminopyridine-4-carboxylate)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
tRNA (guanine-N(1)-)-methyltransferasepolymer24426434.72UniProt (B1MDI3)
Pfam (PF01746)
Mycobacterium abscessusM1G-methyltransferase,tRNA [GM37] methyltransferase
2C, E
(A, B)
methyl 2-azanylpyridine-4-carboxylatenon-polymer152.22Chemie (J9T)
3D, F
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
4G, H
(A, B)
waterwater18.0334Chemie (HOH)
Sequence modifications
A, B: 1 - 242 (UniProt: B1MDI3)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight52869.3
Non-Polymers*Number of molecules4
Total formula weight496.4
All*Total formula weight53365.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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