6QM0

Cathepsin-K in complex with amino-oxaazabicyclo[3.3.0]octanyl containing inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Cathepsin K	polymer	216	23680.7	2	UniProt (P43235) Pfam (PF00112) In PDB	Homo sapiens (Human)	Cathepsin O,Cathepsin O2,Cathepsin X
2	A	(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID	non-polymer		190.2	1	Chemie (MHA)
3	A, B	~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{R},6~{a}~{R})-6-azanyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-3-fluoranyl-4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide	non-polymer		560.7	2	Chemie (J6B)
4		water	water		18.0	528	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47361.3
Non-Polymers*	Number of molecules	3
	Total formula weight	1311.5
All*	Total formula weight	48672.9

*Water molecules are not included.