6QLX

Cathepsin-K in complex with fluoro-oxa-azabicyclo[3.3.0]octanyl containing inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cathepsin K	polymer	216	23680.7	1	UniProt (P43235) Pfam (PF00112) In PDB	Homo sapiens (Human)	Cathepsin O,Cathepsin O2,Cathepsin X
2	A	~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{S},6~{a}~{S})-6-fluoranyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-thiophen-2-yl-benzamide	non-polymer		446.5	1	Chemie (HKH)
3		water	water		18.0	340	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23680.7
Non-Polymers*	Number of molecules	1
	Total formula weight	446.5
All*	Total formula weight	24127.2

*Water molecules are not included.