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6QLD

Structure of inner kinetochore CCAN-Cenp-A complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Inner kinetochore subunit MIF2polymer222754.31UniProt (P35201)Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-C homolog,Constitutive centromere-associated network protein MIF2,Mitotic fidelity of chromosome transmission protein 2
2B
(G)
DNA (125-MER)polymer12438030.21Escherichia coli
3C
(H)
Inner kinetochore subunit MCM16polymer13315815.11UniProt (Q12262)
Pfam (PF20993)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-H homolog,Constitutive centromere-associated network protein MCM16,Minichromosome maintenance protein 16
4D
(I)
Inner kinetochore subunit CTF3polymer40847222.81UniProt (Q12748)Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-I homolog,Chromosome loss protein 3,Chromosome transmission fidelity protein 3,Constitutive centromere-associated network protein CTF3
5E
(J)
DNA (125-MER)polymer12438510.51Escherichia coli
6F
(K)
Inner kinetochore subunit MCM22polymer12214082.11UniProt (P47167)Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-K homolog,Constitutive centromere-associated network protein MCM22,Minichromosome maintenance protein 22
7G
(L)
Inner kinetochore subunit IML3polymer24127644.71UniProt (P38265)Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-L homolog,Constitutive centromere-associated network protein IML3,Increased minichromosome loss protein 3,Minichromosome maintenance protein 19
8H
(N)
Inner kinetochore subunit CHL4polymer44751642.41UniProt (P38907)
Pfam (PF05238)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-N homolog,Chromosome loss protein 4,Chromosome transmission fidelity protein 17,Constitutive centromere-associated network protein CHL4,Minichromosome maintenance protein 17
9I
(O)
Inner kinetochore subunit MCM21polymer21224746.41UniProt (Q06675)
Pfam (PF09496)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-O homolog,Chromosome transmission fidelity protein 5,Constitutive centromere-associated network protein MCM21,Minichromosome maintenance protein 21
10J
(P)
Inner kinetochore subunit CTF19polymer27031659.01UniProt (Q02732)Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-P homolog,Chromosome transmission fidelity protein 19,Constitutive centromere-associated network protein CTF19,Minichromosome maintenance protein 18
11K
(Q)
Inner kinetochore subunit OKP1polymer23127358.41UniProt (P53298)Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-Q homolog,Constitutive centromere-associated network protein OKP1,Outer kinetochore protein 1
12L
(U)
Inner kinetochore subunit AME1polymer19022158.01UniProt (P38313)
Pfam (PF20994)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Associated with microtubules and essential protein 1,CENP-U homolog,Constitutive centromere-associated network protein AME1
13M
(Y)
Inner kinetochore subunit NKP1polymer23726875.31UniProt (Q12493)Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Constitutive centromere-associated network protein NKP1,Non-essential kinetochore protein 1
14N
(Z)
Inner kinetochore subunit NKP2polymer15117631.71UniProt (Q06162)
Pfam (PF09447)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Constitutive centromere-associated network protein NKP2,Non-essential kinetochore protein 2
15O
(a)
Histone H3-like centromeric protein CSE4polymer9010535.41UniProt (P36012)
Pfam (PF00125)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-A homolog,Chromosome segregation protein 4
16P, S
(b, f)
Histone H4polymer798897.32UniProt (P02309)
Pfam (PF15511)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
17Q
(d)
Histone H2B.2polymer9310342.81UniProt (P02294)
Pfam (PF00125)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
18R
(e)
Histone H3-like centromeric protein CSE4polymer11513715.11UniProt (P36012)
Pfam (PF00125)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-A homolog,Chromosome segregation protein 4
19T
(g)
Histone H2A.1polymer10511546.41UniProt (P04911)
Pfam (PF00125)
Pfam (PF16211)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
20U
(h)
Histone H2B.1polymer9410413.81UniProt (P02293)
Pfam (PF00125)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Suppressor of Ty protein 12
21V
(i)
Histone H2A.1polymer10211190.91UniProt (P04911)
Pfam (PF00125)
Pfam (PF16211)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains22
Total formula weight471670.1
All*Total formula weight471670.1
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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