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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6QLD

Structure of inner kinetochore CCAN-Cenp-A complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1CInner kinetochore subunit MIF2polymer222754.31UniProt (P35201)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-C homolog,Constitutive centromere-associated network protein MIF2,Mitotic fidelity of chromosome transmission protein 2
2GDNA (125-MER)polymer12438030.21Escherichia coli
3HInner kinetochore subunit MCM16polymer13315815.11UniProt (Q12262)
Pfam (PF20993)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-H homolog,Constitutive centromere-associated network protein MCM16,Minichromosome maintenance protein 16
4IInner kinetochore subunit CTF3polymer40847222.81UniProt (Q12748)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-I homolog,Chromosome loss protein 3,Chromosome transmission fidelity protein 3,Constitutive centromere-associated network protein CTF3
5JDNA (125-MER)polymer12438510.51Escherichia coli
6KInner kinetochore subunit MCM22polymer12214082.11UniProt (P47167)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-K homolog,Constitutive centromere-associated network protein MCM22,Minichromosome maintenance protein 22
7LInner kinetochore subunit IML3polymer24127644.71UniProt (P38265)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-L homolog,Constitutive centromere-associated network protein IML3,Increased minichromosome loss protein 3,Minichromosome maintenance protein 19
8NInner kinetochore subunit CHL4polymer44751642.41UniProt (P38907)
Pfam (PF05238)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-N homolog,Chromosome loss protein 4,Chromosome transmission fidelity protein 17,Constitutive centromere-associated network protein CHL4,Minichromosome maintenance protein 17
9OInner kinetochore subunit MCM21polymer21224746.41UniProt (Q06675)
Pfam (PF09496)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-O homolog,Chromosome transmission fidelity protein 5,Constitutive centromere-associated network protein MCM21,Minichromosome maintenance protein 21
10PInner kinetochore subunit CTF19polymer27031659.01UniProt (Q02732)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-P homolog,Chromosome transmission fidelity protein 19,Constitutive centromere-associated network protein CTF19,Minichromosome maintenance protein 18
11QInner kinetochore subunit OKP1polymer23127358.41UniProt (P53298)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-Q homolog,Constitutive centromere-associated network protein OKP1,Outer kinetochore protein 1
12UInner kinetochore subunit AME1polymer19022158.01UniProt (P38313)
Pfam (PF20994)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Associated with microtubules and essential protein 1,CENP-U homolog,Constitutive centromere-associated network protein AME1
13YInner kinetochore subunit NKP1polymer23726875.31UniProt (Q12493)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Constitutive centromere-associated network protein NKP1,Non-essential kinetochore protein 1
14ZInner kinetochore subunit NKP2polymer15117631.71UniProt (Q06162)
Pfam (PF09447)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Constitutive centromere-associated network protein NKP2,Non-essential kinetochore protein 2
15aHistone H3-like centromeric protein CSE4polymer9010535.41UniProt (P36012)
Pfam (PF00125)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-A homolog,Chromosome segregation protein 4
16b, fHistone H4polymer798897.32UniProt (P02309)
Pfam (PF15511)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
17dHistone H2B.2polymer9310342.81UniProt (P02294)
Pfam (PF00125)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
18eHistone H3-like centromeric protein CSE4polymer11513715.11UniProt (P36012)
Pfam (PF00125)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)CENP-A homolog,Chromosome segregation protein 4
19gHistone H2A.1polymer10511546.41UniProt (P04911)
Pfam (PF00125)
Pfam (PF16211)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
20hHistone H2B.1polymer9410413.81UniProt (P02293)
Pfam (PF00125)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Suppressor of Ty protein 12
21iHistone H2A.1polymer10211190.91UniProt (P04911)
Pfam (PF00125)
Pfam (PF16211)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains22
Total formula weight471670.1
All*Total formula weight471670.1
*Water molecules are not included.

218853

PDB entries from 2024-04-24

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