6QKZ
Full length GluA1/2-gamma8 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | GluA1 | polymer | 897 | 100739.6 | 2 | UniProt (P19490) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | |
| 2 | B, D (B, D) | Glutamate receptor 2 | polymer | 839 | 93880.1 | 2 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 3 | E, F (I, J) | Voltage-dependent calcium channel gamma-8 subunit | polymer | 423 | 43592.0 | 2 | UniProt (Q8VHW5) Pfam (PF00822) | Rattus norvegicus (Rat) | Neuronal voltage-gated calcium channel gamma-8 subunit,Transmembrane AMPAR regulatory protein gamma-8,TARP gamma-8 |
| 4 | G, K (E, K) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 5 | H, I, J, L, M... (F, G, H, L, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 6 | O, Q, R, T (A, B, C, D) | 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide | non-polymer | 336.3 | 4 | Chemie (E2Q) | |||
| 7 | P, S (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, C: 2 - 889 (UniProt: P19490)
B, D: 1 - 839 (UniProt: P19491)
I, J: 1 - 416 (UniProt: Q8VHW5)
| PDB | External Database | Details |
|---|---|---|
| Ala -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Lys 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Arg 586 | Gln 607 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 116 | Ala 117 | conflict |
| Leu 417 | - | expression tag |
| Glu 418 | - | expression tag |
| Val 419 | - | expression tag |
| Leu 420 | - | expression tag |
| Phe 421 | - | expression tag |
| Gln 422 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 476423.4 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 3719.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1787.5 | |
| All* | Total formula weight | 481930.4 |
