6QKK

Aplysia californica AChBP in complex with 2-Fluoro-(carbamoylpyridinyl)deschloroepibatidine analogue (1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Soluble acetylcholine receptor	polymer	249	28326.8	10	UniProt (Q8WSF8) Pfam (PF02931)	Aplysia californica (California sea hare)
2	DB, EA, IB, K, MA... (H, D, I, A, E...)	4-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]benzamide	non-polymer		311.4	10	Chemie (H92)
3	EB, FA, JB, L, NA... (H, D, I, A, E...)	PHOSPHATE ION	non-polymer		95.0	10	Chemie (PO4)
4	AA, AB, BA, BB, CA... (C, G, H, D, I...)	1,2-ETHANEDIOL	non-polymer		62.1	40	Chemie (EDO)
5	JA, OB, P, WB (D, I, A, J)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
6	T (B)	OXALATE ION	non-polymer		88.0	1	Chemie (OXL)
7	AC, BC, CC, DC, EC... (D, E, F, G, H...)	water	water		18.0	1138	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 1 - 236 (UniProt: Q8WSF8)

PDB	External Database	Details
Val 60	Ala 60	conflict
Val 155	Ala 155	conflict
Glu 237	-	expression tag
Asn 238	-	expression tag
Leu 239	-	expression tag
Tyr 240	-	expression tag
Phe 241	-	expression tag
Gln 242	-	expression tag
Gly 243	-	expression tag
His 244	-	expression tag
His 245	-	expression tag
His 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	283267.5
Non-Polymers*	Number of molecules	65
	Total formula weight	7518.8
All*	Total formula weight	290786.3

*Water molecules are not included.