6QIG
Metalloproteinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Antibody Light Chain | polymer | 213 | 23508.8 | 1 | Rattus norvegicus | ||
| 2 | B (H) | Antibody Heavy Chain | polymer | 227 | 24437.3 | 1 | Rattus norvegicus | ||
| 3 | C (A) | A disintegrin and metalloproteinase with thrombospondin motifs 13 | polymer | 604 | 65795.2 | 1 | UniProt (Q76LX8) Pfam (PF01421) Pfam (PF17771) Pfam (PF00090) Pfam (PF19236) Pfam (PF05986) | Homo sapiens (Human) | ADAMTS-13,von Willebrand factor-cleaving protease,vWF-cleaving protease |
| 4 | D (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, H (C, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F (D) | alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G08918EL) | |||
| 7 | G (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G79924RM) | |||
| 8 | I, J, O, P, Y (L, H, A) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 9 | AA, BA, DA, K, M... (A, L, H) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 8 | Chemie (PEG) | |||
| 10 | CA, L (A, L) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 11 | N (H) | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) | |||
| 12 | S (A) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 13 | T (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 14 | U (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 15 | V, W, X (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 16 | EA, FA, GA (L, H, A) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 79 - 682 (UniProt: Q76LX8)
| PDB | External Database | Details |
|---|---|---|
| Gln 225 | Glu 225 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 113741.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2608.4 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 1961.6 | |
| All* | Total formula weight | 118311.3 |
