6QEE
Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ABCB1HM-EQ | polymer | 1300 | 143627.8 | 1 | Homo sapiens | ||
2 | B | UIC2 Antigen Binding Fragment Light chain | polymer | 220 | 24321.0 | 1 | Mus musculus | ||
3 | C | UIC2 Antigen Binding Fragment Heavy Chain | polymer | 225 | 24381.3 | 1 | Mus musculus | ||
4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
5 | A | Zosuquidar | non-polymer | 527.6 | 2 | Chemie (ZQU) | |||
6 | A | CHOLESTEROL | non-polymer | 386.7 | 7 | Chemie (CLR) | |||
7 | A | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE | non-polymer | 748.1 | 1 | Chemie (3PE) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 192330.1 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 5173.5 | |
All* | Total formula weight | 197503.6 |