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6QEE

Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AABCB1HM-EQpolymer1300143627.81Homo sapiens
2BUIC2 Antigen Binding Fragment Light chainpolymer22024321.01Mus musculus
3CUIC2 Antigen Binding Fragment Heavy Chainpolymer22524381.31Mus musculus
4A2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
5AZosuquidarnon-polymer527.62Chemie (ZQU)
6ACHOLESTEROLnon-polymer386.77Chemie (CLR)
7A1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINEnon-polymer748.11Chemie (3PE)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight192330.1
Non-Polymers*Number of molecules13
Total formula weight5173.5
All*Total formula weight197503.6
*Water molecules are not included.

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PDB entries from 2024-09-11

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