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6QEE

Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ABCB1HM-EQpolymer1300143627.81Homo sapiens
2B
(B)
UIC2 Antigen Binding Fragment Light chainpolymer22024321.01Mus musculus
3C
(C)
UIC2 Antigen Binding Fragment Heavy Chainpolymer22524381.31Mus musculus
4D, E, F
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
5G, H
(A)
Zosuquidarnon-polymer527.62Chemie (ZQU)
6I, J, K, L, M...
(A)
CHOLESTEROLnon-polymer386.77Chemie (CLR)
7P
(A)
1,2-Distearoyl-sn-glycerophosphoethanolaminenon-polymer748.11Chemie (3PE)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight192330.1
Non-Polymers*Number of molecules13
Total formula weight5173.5
All*Total formula weight197503.6
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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