6QD5
X-ray Structure of the Human Urea Channel SLC14A1/UT1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Urea transporter 1 | polymer | 367 | 40177.4 | 1 | UniProt (Q13336) Pfam (PF03253) | Homo sapiens (Human) | Solute carrier family 14 member 1,Urea transporter,erythrocyte |
| 2 | B, C, D, E, F... (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 7 | Chemie (BOG) | |||
| 3 | I (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) | |||
| 4 | J, K (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 5 | L (A) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 31 - 389 (UniProt: Q13336)
| PDB | External Database | Details |
|---|---|---|
| Met 30 | - | initiating methionine |
| Val 167 | Met 167 | variant |
| Gln 211 | Asn 211 | engineered mutation |
| Asn 280 | Asp 280 | variant |
| Ala 390 | - | expression tag |
| Glu 391 | - | expression tag |
| Asn 392 | - | expression tag |
| Leu 393 | - | expression tag |
| Tyr 394 | - | expression tag |
| Phe 395 | - | expression tag |
| Gln 396 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40177.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2921.8 | |
| All* | Total formula weight | 43099.2 |
