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6QB6

Mcl1 in complex with a Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Induced myeloid leukemia cell differentiation protein Mcl-1polymer16218227.61UniProt (Q07820)
Pfam (PF00452)
Homo sapiens (Human)Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT
2B
(H)
Fab Heavy Chainpolymer23024488.51Homo sapiens
3C
(L)
Fab Light Chainpolymer22023494.71Homo sapiens
4D, E, F
(A, H, L)
waterwater18.0154Chemie (HOH)
Sequence modifications
A: 174 - 327 (UniProt: Q07820)
PDBExternal DatabaseDetails
Gly 166-expression tag
Pro 167-expression tag
Leu 168-expression tag
Gly 169-expression tag
Ser 170-expression tag
Glu 171-expression tag
Asp 172-expression tag
Asp 173-expression tag
Ser 193Ala 193conflict
Ser 196Thr 196conflict
Leu 199Met 199conflict
Glu 201Arg 201conflict
Ala 202Ser 202conflict
Ala 205Thr 205conflict
Gly 206Ser 206conflict
Arg 208Lys 208conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight66210.8
All*Total formula weight66210.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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