6QAS
Crystal structure of ULK1 in complexed with PF-03814735
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase ULK1 | polymer | 287 | 32400.2 | 2 | UniProt (O75385) Pfam (PF00069) | Homo sapiens (Human) | Autophagy-related protein 1 homolog,hATG1,Unc-51-like kinase 1 |
| 2 | C, D, E, U, V... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | F, X (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 4 | AA, BA, CA, G, H... (B, A) | GLYCEROL | non-polymer | 92.1 | 11 | Chemie (GOL) | |||
| 5 | DA, EA, FA, GA, HA... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 6 | IA, JA, T (B, A) | N-{2-[(1S,4R)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide | non-polymer | 474.5 | 3 | Chemie (34W) | |||
| 7 | KA, LA (A, B) | water | water | 18.0 | 385 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 283 (UniProt: O75385)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 37 | Glu 37 | conflict |
| Ala 38 | Lys 38 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64800.5 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 4141.9 | |
| All* | Total formula weight | 68942.4 |
