6Q9Y
HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 16 AT 1.20A; Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Protein Mdm4 | polymer | 100 | 11187.0 | 2 | UniProt (O15151) In PDB | Homo sapiens (Human) | Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4 |
| 2 | A, B | 7-methoxy-~{N}-[(3~{S})-1-(4-methylphenyl)pyrrolidin-3-yl]-1~{H}-indole-3-carboxamide | non-polymer | 349.4 | 2 | Chemie (HRQ) | |||
| 3 | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A, B: 15 - 112 (UniProt: O15151)
| PDB | External Database | Details |
|---|---|---|
| Gly 13 | - | expression tag |
| Pro 14 | - | expression tag |
| Ser 18 | Cys 17 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22374.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 698.9 | |
| All* | Total formula weight | 23072.8 |
