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6Q9Y

HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 16 AT 1.20A; Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0043066biological_processnegative regulation of apoptotic process
A0051726biological_processregulation of cell cycle
B0005634cellular_componentnucleus
B0043066biological_processnegative regulation of apoptotic process
B0051726biological_processregulation of cell cycle
Functional Information from PDB Data
site_idAC1
Number of Residues13
Detailsbinding site for residue HRQ A 201
ChainResidue
AGLY58
BVAL93
BLYS94
BPRO96
BHRQ201
AILE61
ATYR67
AGLN72
AVAL75
APHE91
AVAL93
ALEU99
BHIS73

site_idAC2
Number of Residues14
Detailsbinding site for residue HRQ B 201
ChainResidue
AHIS73
AVAL93
ALYS94
APRO96
AHRQ201
BGLY58
BILE61
BTYR67
BGLN72
BVAL75
BPHE91
BVAL93
BLEU99
BLEU103

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PDB entries from 2024-11-13

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