6Q9Y
HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 16 AT 1.20A; Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005634 | cellular_component | nucleus |
A | 0043066 | biological_process | negative regulation of apoptotic process |
A | 0051726 | biological_process | regulation of cell cycle |
B | 0005634 | cellular_component | nucleus |
B | 0043066 | biological_process | negative regulation of apoptotic process |
B | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | binding site for residue HRQ A 201 |
Chain | Residue |
A | GLY58 |
B | VAL93 |
B | LYS94 |
B | PRO96 |
B | HRQ201 |
A | ILE61 |
A | TYR67 |
A | GLN72 |
A | VAL75 |
A | PHE91 |
A | VAL93 |
A | LEU99 |
B | HIS73 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue HRQ B 201 |
Chain | Residue |
A | HIS73 |
A | VAL93 |
A | LYS94 |
A | PRO96 |
A | HRQ201 |
B | GLY58 |
B | ILE61 |
B | TYR67 |
B | GLN72 |
B | VAL75 |
B | PHE91 |
B | VAL93 |
B | LEU99 |
B | LEU103 |