6Q94
Crystal structure of human GDP-D-mannose 4,6-dehydratase (S156D) in complex with GDP-Man
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A, C, D, E... | GDP-mannose 4,6 dehydratase | polymer | 352 | 40084.5 | 8 | UniProt (O60547) Pfam (PF16363) In PDB | Homo sapiens (Human) | GDP-D-mannose dehydratase,GMD |
2 | B, A, C, D, E... | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 8 | Chemie (NAP) | |||
3 | H, B, A, C, D... | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE | non-polymer | 605.3 | 8 | Chemie (GDD) | |||
4 | H, D, G | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
5 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
B, A, C, D, E, F, G, H: 23 - 372 (UniProt: O60547)
PDB | External Database | Details |
---|---|---|
Ser 21 | - | expression tag |
Met 22 | - | expression tag |
Asp 156 | Ser 156 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 320675.8 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 11038.2 | |
All* | Total formula weight | 331714.0 |