6Q3X
Structure of human galactokinase in complex with galactose and 2'-(benzo[d]oxazol-2-ylamino)-7',8'-dihydro-1'H-spiro[cyclohexane-1,4'-quinazolin]-5'(6'H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galactokinase | polymer | 393 | 42348.1 | 2 | UniProt (P51570) Pfam (PF10509) Pfam (PF00288) Pfam (PF08544) | Homo sapiens (Human) | Galactose kinase |
| 2 | C, H (A, B) | beta-D-galactopyranose | non-polymer | 180.2 | 2 | Chemie (GAL) | |||
| 3 | D, E, F, I, J (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
| 4 | G, K (A, B) | 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one | non-polymer | 350.4 | 2 | Chemie (HFK) PubChem (1294862) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 392 (UniProt: P51570)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Ala 252 | Lys 252 | conflict |
| Ala 253 | Glu 253 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84696.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1652.0 | |
| All* | Total formula weight | 86348.2 |
